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Une histoire de mots inattendus et de génomes

By Sophie Schbath

Also appears in collection : ALEA Days 2017 / Journées ALEA 2017

Dans une première partie, je présenterai différentes problématiques liées à des statistiques d'occurrences de mots dans des génomes et décortiquerai plus en détail la question de savoir comment détecter si un mot a une fréquence d'apparition significativement anormale dans une séquence. Dans une deuxième partie, je présenterai différentes extensions pour tenir compte du fait qu'un motif d'ADN fonctionnel n'est pas toujours un « mot », mais qu'il peut avoir une structure plus complexe qui nécessite le développement de nouvelles méthodes statistiques.

Information about the video

Date of recording 22/03/2017
Date of publication 30/03/2017
Institution CIRM
Licence CC BY NC ND
Language English
Audience Researchers, Graduate Students
Director(s) Guillaume Hennenfent
Format MP4

Citation data

DOI 10.24350/CIRM.V.19146403
Cite this video Schbath, Sophie (22/03/2017). Une histoire de mots inattendus et de génomes. CIRM. Audiovisual resource. DOI: 10.24350/CIRM.V.19146403
URL https://dx.doi.org/10.24350/CIRM.V.19146403

Domain(s)

Bibliography

Reinert, G., Schbath, S., & Waterman, M. (2005). Statistics on Words with Applications to Biological Sequences. In Applied Combinatorics on Words (pp. 251-328). Cambridge: Cambridge University Press - http://www-igm.univ-mlv.fr/~berstel/Lothaire/
Reinert, G., Schbath, S., & Waterman, M. (2000). Probabilistic and statistical properties of words. Journal of Computational Biology, 7, 1-46 - http://genome.jouy.inra.fr/%7Eschbath/papiers/RSW00.ps
Robin, S., Rodolphe, F., & Schbath, S. (2005). DNA, Words and Models. Statistics of exceptional words. Cambridge: Cambridge University Press - http://www.cambridge.org/uk/catalogue/catalogue.asp?isbn=052184729X
Robin, S., Rodolphe, F. and Schbath, S. (2003). ADN, mots et modèles. Paris : Belin - https://www.belin-education.com/adn-mots-et-modeles
Schbath, S., & Robin, R. (2009). How pattern statistics can be useful for DNA motif discovery? In J. Glaz, I. Pozdnyakov, & S. Wallenstein (Eds.), Scan Statistics. Methods and Applications (pp. 319-350). Boston, MA: Birkhäuser - http://dx.doi.org/10.1007/978-0-8176-4749-0_15

MSC codes

Document(s)

http://gt-alea.math.cnrs.fr/alea2017/slides/ALEA2017_Schbath.pdf

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