Sparse multiple testing: can one estimate the null distribution ?
When performing multiple testing, adjusting the distribution of the null hypotheses is ubiquitous in applications. However, the effect of such an operation remains largely unknown, especially in terms of false discovery proportion (FDP) and true discovery proportion (TDP). In this talk, we explore this issue in the most classical case where the null distributions are Gaussian with an unknown rescaling parameters (mean and variance) and where the Benjamini-Hochberg (BH) procedure is applied after a datarescaling step.