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From data to biological processes: interactions, networks and analyses, to understand cellular functions

By Christine Brun

Appears in collection : Thematic Month Week 5: Networks and Molecular Biology / Mois thématique Semaine 5 : Réseaux et biologie moléculaire

Basics on the biology of molecular interactions and interaction data will be given all along the presentation of some of our research projects.

Information about the video

Citation data

  • DOI 10.24350/CIRM.V.19619603
  • Cite this video Brun, Christine (02/03/2020). From data to biological processes: interactions, networks and analyses, to understand cellular functions. CIRM. Audiovisual resource. DOI: 10.24350/CIRM.V.19619603
  • URL https://dx.doi.org/10.24350/CIRM.V.19619603

Bibliography

  • BECKER, Emmanuelle, ROBISSON, Benoît, CHAPPLE, Charles E., et al. Multifunctional proteins revealed by overlapping clustering in protein interaction network. Bioinformatics, 2012, vol. 28, no 1, p. 84-90. - https://doi.org/10.1093/bioinformatics/btr621
  • CHAPPLE, Charles E., HERRMANN, Carl, et BRUN, Christine. PrOnto database: GO term functional dissimilarity inferred from biological data. Frontiers in genetics, 2015, vol. 6, p. 200. - https://doi.org/10.3389/fgene.2015.00200
  • CHAPPLE, Charles E., ROBISSON, Benoit, SPINELLI, Lionel, et al. Extreme multifunctional proteins identified from a human protein interaction network. Nature communications, 2015, vol. 6, no 1, p. 1-9. - http://dx.doi.org/10.1038/ncomms8412
  • ZANZONI, Andreas, RIBEIRO, Diogo M., et BRUN, Christine. Understanding protein multifunctionality: from short linear motifs to cellular functions. Cellular and Molecular Life Sciences, 2019, p. 1-6. - http://dx.doi.org/10.1007/s00018-019-03273-4
  • BALTZ, Alexander G., MUNSCHAUER, Mathias, SCHWANHÄUSSER, Björn, et al. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Molecular cell, 2012, vol. 46, no 5, p. 674-690. - https://doi.org/10.1016/j.molcel.2012.05.021
  • BECKMANN, Benedikt M., CASTELLO, Alfredo, et MEDENBACH, Jan. The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions. Pflügers Archiv-European Journal of Physiology, 2016, vol. 468, no 6, p. 1029-1040. - https://doi.org/10.1007/s00424-016-1819-4
  • HENTZE, Matthias W., CASTELLO, Alfredo, SCHWARZL, Thomas, et al. A brave new world of RNA-binding proteins. Nature Reviews Molecular Cell Biology, 2018, vol. 19, no 5, p. 327. - https://doi.org/10.1038/nrm.2017.130
  • RIBEIRO, António J. M., HOLLIDAY, Gemma L., FURNHAM, Nicholas, et al. Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites. Nucleic acids research, 2018, vol. 46, no D1, p. D618-D623. - https://doi.org/10.1093/nar/gkx1012

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